Genome-wide association study of the fatty liver index in the Taiwanese population reveals shared and population-specific genetic risk factors across ethnicities

Table 1 Baseline characteristics of the TWB study cohort

Characteristics	All Subjects	Cases	Controls	P value
Number of samples	145,356	18,479	126,877
Sex, men (%)	36.22	63.02	32.32	< 0.001
Age, yr	49.42 ± 11.38	48.67 ± 10.97	49.53 ± 11.43	< 0.001
Height, cm	162.09 ± 8.33	165.74 ± 8.91	161.55 ± 8.11	< 0.001
Weight, kg	64.06 ± 12.96	83.17 ± 13.03	61.29 ± 10.34	< 0.001
BMI, kg/m²	24.27 ± 3.85	30.23 ± 3.80	23.40 ± 2.99	< 0.001
Waistline, cm	83.40 ± 10.36	99.02 ± 8.72	81.12 ± 8.44	< 0.001
Total cholesterol, mg/dL	195.81 ± 37.07	203.22 ± 39.57	194.72 ± 36.56	< 0.001
Triglycerides, mg/dL	115.77 ± 94.27	225.98 ± 185.04	99.71 ± 56.29	< 0.001
HDL-C, mg/dL	54.85 ± 13.54	44.17 ± 9.71	56.41 ± 13.32	< 0.001
LDL-C, mg/dL	120.88 ± 31.90	125.15 ± 34.95	120.26 ± 31.39	< 0.001
Gamma GT, U/L	24.16 ± 31.52	54.24 ± 70.06	19.78 ± 16.50	< 0.001
SGOT, U/L	24.56 ± 12.95	31.87 ± 19.20	23.51 ± 11.39	< 0.001
SGPT, U/L	24.07 ± 21.32	43.03 ± 33.07	21.31 ± 17.37	< 0.001
FLI	25.92 ± 24.67	76.71 ± 10.93	18.53 ± 15.79	< 0.001
Alcohol consumption
Yes	8,840	2,455	6,385
No	136,401	16,010	120,391

ISSN: 2045-3701