Fig. 3
From: Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability
Silencing EPN3 inhibits the migration and invasion of NSCLC cells in vitro.A Scratch wound healing assay investigating the migration ability of A549 and H1975 cells after EPN3 silencing. Scale bar, 100 μm. B Quantification of the wound closure area (n = 3). C Transwell assay evaluating the migration and invasion of A549 and H1975 cells after EPN3 silencing. Scale bar, 100 μm. D Quantification of the number of migrated and invaded cells (n = 3). E Protein expression levels of E-cadherin, N-cadherin, vimentin and EPN3 (n = 3). The protein expression levels were normalized to those of β-tubulin in each sample. Data are presented as the mean ± SD. **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. control group